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Rad21ltm1Amp
Targeted Allele Detail
Summary
Symbol: Rad21ltm1Amp
Name: RAD21-like (S. pombe); targeted mutation 1, Alberto M Pendas
MGI ID: MGI:5292341
Gene: Rad21l  Location: Chr2:151487324-151510453 bp, - strand  Genetic Position: Chr2, 74.83 cM
Alliance: Rad21ltm1Amp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176168
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Duplication, Insertion
  Rad21ltm1Amp involves 1 genes/genome features (Rad21l) View all
 
Mutation detailsA targeting vector inserted Hprt and neo cassettes and duplicated exons 4 through 9. The absence of protein expression was confirmed by western blot analysis on testis extracts. (J:176168)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rad21l Mutation:  34 strains or lines available
References
Original:  J:176168 Herran Y, et al., The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility. EMBO J. 2011;30(15):3091-105
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory