Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(SOD1*G127X)832Mrkl
Name:	transgene insertion 832, Stefan L Marklund
MGI ID:	MGI:5286589
Transgene:	Tg(SOD1*G127X)832Mrkl  Location: unknown
Alliance:	Tg(SOD1*G127X)832Mrkl page

Strain of Origin:

C57BL/6 x CBA

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(SOD1*G127X)832Mrkl expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human SOD1 (6647) Sod1  (MGI:98351)   Mutation details: An 11.6 kb human SOD1 genomic fragment containing a mutation in exon 5 (Gly127insTGGG) that results in production of a truncated enzyme subunit with five novel amino acids following Gly127 was randomly inserted. This line carries 28 copies of the transgene. (J:175594)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:175594 Jonsson PA, et al., Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis. Brain. 2004 Jan;127(Pt 1):73-88
All:	1 reference(s)