Gene Expression Data
Assay Details
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Assay
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Reference:
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J:58825
Elefanty AG, et al., SCL expression in the mouse embryo detected with a targeted lacZ reporter gene demonstrates its localization to hematopoietic, vascular, and neural tissues. Blood. 1999 Dec 1;94(11):3754-63
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5286069
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Gene symbol:
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Tal1
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Gene name:
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T cell acute lymphocytic leukemia 1
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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E7.5-11.5 embryos were fixed in 0.2% glutaraldehyde; older embryos were fixed in 0.2% glutaraldehyde/1% formaldehyde.
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Results
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Specimen
1.A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 7.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: blood island |
Present |
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1A
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Based on the speckled staining pattern, expression is believed to be present in the blood islands.
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Specimen
1.B:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 7.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Glutaraldehyde
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Embedding:
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Cryosection
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Specimen
1.C left:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: blood vessel |
Present |
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1C
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Expression is present in the angioblasts of the cerebral vascular plexus.
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| TS12: allantois |
Present |
Regionally restricted |
1C
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Expression is present in the angioblasts of the allantoic vascular plexus.
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| TS12: dorsal aorta |
Present |
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1C
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Expression is present in the angioblasts.
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| TS12: endocardial tube |
Present |
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1C
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Expression is present in the endocardium.
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Specimen
1.D left:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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Specimen
1.E:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: dorsal aorta |
Present |
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1E
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Expression is present in the angioblasts.
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| TS12: vitelline vein |
Present |
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1E
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Expression is present in the angioblasts.
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| TS12: allantois |
Present |
Regionally restricted |
1E
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Expression is present in the angioblasts forming the allantoic vascular plexus.
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Specimen
1.F:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: arterial system |
Present |
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1F
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Expression is present in the somitic arteries sprouting from the dorsal aorta.
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Specimen
2.A:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: dorsal aorta |
Present |
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2A
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Expression is present in the angioblasts.
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| TS12: blood vessel |
Present |
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2A
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Expression is present in the angioblasts forming the cerebral vascular plexus.
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Specimen
2.B:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: endocardial tube |
Present |
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2B
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Expression is present in the endocardium.
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Specimen
2.C:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1tm2Wehi
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Age:
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embryonic day 8.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: arterial system |
Present |
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2C
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Expression is present in the somitic arteries.
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Specimen
5.B:
embryonic day 11.5; Tal1tm2Wehi/Tal1 +
(more  )
Specimen
5.B:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Glutaraldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural tube lateral wall |
Weak |
Regionally restricted |
5B
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Expression is present in the presumptive motor neurons in the ventral neural tube.
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Specimen
5.C:
embryonic day 12.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.C:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: midbrain |
Present |
Regionally restricted |
5C
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Expression is present laterally in the tegmentum and in the fiber tracts of the posterior commissure.
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Specimen
5.D:
embryonic day 12.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.D:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: midbrain |
Present |
Regionally restricted |
5D
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Expression is present laterally in the tegmentum and in the fiber tracts of the posterior commissure.
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Specimen
5.E:
embryonic day 13.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.E:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
Regionally restricted |
5E
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Expression encompasses most of the tectum and the tegmentum.
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Specimen
5.F:
embryonic day 13.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.F:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: midbrain |
Present |
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5F
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Expression encompasses most of the tectum and the tegmentum.
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Specimen
5.G:
embryonic day 18.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.G:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: inferior colliculus |
Present |
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5G
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS26: superior colliculus |
Present |
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5G
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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Specimen
5.H:
embryonic day 18.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.H:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: inferior colliculus |
Present |
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5H
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS26: superior colliculus |
Present |
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5H
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS26: hindbrain |
Weak |
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5H
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Expression is present in tracts on the ventral surface of the hindbrain.
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Specimen
5.I:
postnatal adult; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.I:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: inferior colliculus |
Present |
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5I
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS28: superior colliculus |
Present |
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5I
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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Specimen
5.J:
postnatal adult; Tal1tm2Wehi/Tal1 +
(more )
Specimen
5.J:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: inferior colliculus |
Present |
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5J
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS28: superior colliculus |
Present |
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5J
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Expression levels are stronger in the superior colliculi than the inferior colliculi.
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| TS28: hindbrain |
Weak |
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5J
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Expression is present in tracts on the ventral surface of the hindbrain.
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Specimen
Not shown:
postnatal adult; Tal1tm2Wehi/Tal1 +
(more )
Specimen
Not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: tectum |
Present |
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Expression is present in the cortical radiations and descending tracts from the tectum.
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Specimen
6.A:
embryonic day 9.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
6.A:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Tal1tm2Wehi/Tal1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: blood |
Present |
Non-Uniform |
6A
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Expression is present in variable intensity in circulating hematopoietic cells.
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Specimen
6.B:
embryonic day 13.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
6.B:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
|
Mutant Allele(s):
|
Tal1tm2Wehi/Tal1+
|
|
Age:
|
embryonic day 13.5
|
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Sex:
|
Not Specified
|
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Type:
|
whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: blood |
Present |
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6B
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Expression is present in definitive erythrocytes.
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Specimen
6.C:
embryonic day 13.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
6.C:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
|
Mutant Allele(s):
|
Tal1tm2Wehi/Tal1+
|
|
Age:
|
embryonic day 13.5
|
|
Sex:
|
Not Specified
|
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Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS21: arterial system |
Weak |
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6C
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Expression is present in the endothelium (here of a cerebral artery).
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Specimen
6.D:
embryonic day 11.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
6.D:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
|
Mutant Allele(s):
|
Tal1tm2Wehi/Tal1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: dorsal aorta |
Present |
Regionally restricted |
6D
|
Expression is present in the enothelium.
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| TS19: blood |
Present |
|
6D
|
Expression is present in a cluster of hematopoietic cells present along the ventrolateral aortic wall.
|
Specimen
6.F:
embryonic day 11.5; Tal1tm2Wehi/Tal1 +
(more )
Specimen
6.F:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
|
Mutant Allele(s):
|
Tal1tm2Wehi/Tal1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: liver |
Strong |
Non-Uniform |
6F
|
There is strong expression in the large megakaryocytes and weaker expression in the smaller erythroblasts.
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Analysis Tools
