Gene Expression Data
Assay Details
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Assay
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Reference:
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J:49839
Zhu Y, et al., Smad3 mutant mice develop metastatic colorectal cancer. Cell. 1998 Sep 18;94(6):703-14
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5014823
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Gene symbol:
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Smad3
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Gene name:
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SMAD family member 3
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2B:
embryonic day 11.5; Smad3tm1Par/Smad3 +
(more  )
Specimen
2B:
(close  )
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Genetic Background:
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either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
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Mutant Allele(s):
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Smad3tm1Par/Smad3+
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: embryo |
Present |
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2B
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Expression was in many developing tissues with highest level in mesenchymal derivatives.
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Specimen
2D:
postnatal adult; Smad3tm1Par/Smad3 +
(more )
Specimen
2D:
(close )
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Genetic Background:
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either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
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Mutant Allele(s):
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Smad3tm1Par/Smad3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: colon |
Present |
Graded |
2D
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Highest expression levels in the muscularis propria and the submucosa and lower levels in the epithelium.
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| TS28: colon epithelium |
Present |
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2D
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Analysis Tools
