Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dppa3tm1(cre)Peli
Name:	developmental pluripotency-associated 3; targeted mutation 1, Pentao Liu
MGI ID:	MGI:5004882
Synonyms:	Stella-cre
Gene:	Dppa3  Location: Chr6:122603383-122607230 bp, + strand  Genetic Position: Chr6, 57.72 cM
Alliance:	Dppa3tm1(cre)Peli page

Germline Transmission:	Earliest citation of germline transmission: J:172071
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Dppa3tm1(cre)Peli expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Dppa3 (MGI:1920958)   Mutation details: A targeting vector was generated by recombineering of a 129S5 BAC to contain an IRES-cre-Frt-Neo-Frt sequence. Homologous recombination in AB2.2 ES cells inserted the IRES-cre into the 3' untranslated region of Dppa3. Germline chimeras were bred to 129S5 females to generated heterozygotes. (J:175778)

Activity:	Tissue activity of this recombinase allele
Driver:	Dppa3 (mouse) Summary of all recombinase alleles driven by Dppa3. Alliance mouse Dppa3 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dppa3 Mutation:	22 strains or lines available

Original:	J:172071 Vassiliou GS, et al., Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet. 2011 May;43(5):470-5
All:	7 reference(s)