Spink2Gt(327A6)Cmhd
Gene trapped Allele Detail
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Symbol: |
Spink2Gt(327A6)Cmhd |
Name: |
serine peptidase inhibitor, Kazal type 2; gene trap 327A6, Centre for Modeling Human Disease |
MGI ID: |
MGI:4966113 |
Synonyms: |
Spink2gt |
Gene: |
Spink2 Location: Chr5:77352954-77359318 bp, - strand Genetic Position: Chr5, 41.53 cM
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Alliance: |
Spink2Gt(327A6)Cmhd page
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Degeneration of germ cells in Spink2Gt(327A6)Cmhd/Spink2Gt(327A6)Cmhd seminferous tubules
Show the 5 phenotype image(s) involving this allele.
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: UPA
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Mutation details: The gene trap inserted upstream of exon 1 and resulted in a transcript containing the gene trap fused to exon 2. A 75% reduction in protein expression was confirmed by western blot analysis. This allele is hypomorphic.
(J:175913)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
42 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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Generation of the 4966113 allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Spink2 Mutation: |
14 strains or lines available
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Original: |
J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008; |
All: |
2 reference(s) |
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