Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Grid2tm1(cre)Mwa
Name:	glutamate receptor, ionotropic, delta 2; targeted mutation 1, Masahiko Watanabe
MGI ID:	MGI:4949272
Synonyms:	D2CreN, GluD2Cre, Grid2Cre
Gene:	Grid2  Location: Chr6:63232860-64681307 bp, + strand  Genetic Position: Chr6, 29.77 cM
Alliance:	Grid2tm1(cre)Mwa page

Germline Transmission:	Earliest citation of germline transmission: J:170673
Parent Cell Line:	RENKA (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Null/knockout, Recombinase) Mutation:    Insertion   Grid2tm1(cre)Mwa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Grid2 (MGI:95813)     The cre sequence and an FRT-flanked neo cassette were inserted at the start codon. (J:170673)

Activity:	Tissue activity of this recombinase allele
Driver:	Grid2 (mouse) Summary of all recombinase alleles driven by Grid2. Alliance mouse Grid2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grid2 Mutation:	85 strains or lines available

Original:	J:170673 Yamasaki M, et al., Glutamate receptor delta2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells. J Neurosci. 2011 Mar 2;31(9):3362-74
All:	14 reference(s)