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Gene Expression Data
Assay Details
Assay
Reference: J:106092 Tissir F, et al., Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
Assay type: RNA in situ
MGI Accession ID: MGI:4946665
Gene symbol: Dvl3
Gene name: dishevelled segment polarity protein 3
Probe: Dvl3 cDNA1
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 1E

Specimen 2M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Moderate Widespread 2M
TS20: cerebellum primordium Strong 2M
TS20: dorsal root ganglion Strong 2M

Specimen 2N & 2O: embryonic day 12.5 (more )
Note: Fig. 2O is a higher magnification image of the boxed region if Fig. 2N.
Structure Level Pattern Image Note
TS20: brain Present Non-Uniform 2O , 2N Expression signal was more intense in postmitotic differentiation fields than in the ventricular zone.
TS20: brain ventricular layer Present Non-Uniform 2O , 2N Expression signal was more intense in postmitotic differentiation fields than in the ventricular zone.

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Moderate 3E
TS22: brain Present Regionally restricted 3E Expression was detected in ventricular zone and post-migratory neuronal fields, with the highest signal in the latter.
TS22: brain ventricular layer Present Regionally restricted 3E Expression was detected in ventricular zone and post-migratory neuronal fields, with the highest signal in the latter.

Specimen Table 2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brainstem Ambiguous Regionally restricted Expression was very low or undetectable in the reticular formation and the cochleovestibular nuclei.
TS25: cerebellum Present Regionally restricted Expression was present in the external granule layer.
TS25: midbrain tegmentum Ambiguous Expression was very low or undetectable.
TS25: midbrain ventricular layer Ambiguous Expression was very low or undetectable.
TS25: tectum Ambiguous Expression was very low or undetectable.
TS25: diencephalon ventricular layer Present
TS25: hypothalamus Present
TS25: thalamus Present Expression was detected in the dorsal and ventral thalamus.
TS25: retina Present Regionally restricted Expression was detected in the ventricular zone and the ganglion cells.
TS25: cortical plate Present Regionally restricted Expression was detected in the cortical plate ventricular zone/subventricular zone and in the cortical plate proper.
TS25: corpus striatum Present Regionally restricted Expression was detected in the striatum ventricular zone/subventricular zone and was very low or undetectable in the striatum.
TS25: main olfactory bulb Present Regionally restricted Expression was detected in the olfactory bulb. Expression was very low or undetectable in the mitral cells.

Specimen 4E1: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Moderate 4E1
TS25: cerebellum Moderate Regionally restricted 4E1 Expression was detected in the external granule layer.

Specimen 4E2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Moderate 4E2
TS25: telencephalon ventricular layer Moderate 4E2

Specimen 4E3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Moderate 4E3
TS25: telencephalon ventricular layer Moderate 4E3

Specimen 4E4: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: skin Weak 4E4

Specimen 5H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain ventricular layer Weak 5H
TS27: cerebral cortex Strong Regionally restricted 5H Expression was strong in the cortical plate.
TS27: cerebellum external granule cell layer Strong 5H
TS27: hippocampus Strong 5H

Specimen Table 3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present
TS28: dentate gyrus Present
TS28: hippocampus pyramidal cell layer Present
TS28: diencephalon Ambiguous Regionally restricted Expression was very low or undetectable in the diencephalon ventricular zone.
TS28: dorsal thalamus Ambiguous Expression was very low or undetectable.
TS28: hypothalamus Ambiguous Expression was very low or undetectable.
TS28: main olfactory bulb granule cell layer Ambiguous Expression was very low or undetectable.
TS28: main olfactory bulb mitral cell layer Ambiguous Expression was very low or undetectable.
TS28: prethalamus Ambiguous Expression was very low or undetectable.
TS28: cerebral cortex Present Regionally restricted Expression was detected in the cortical plate ventricular zone/subventricular zone and the cortical plate proper.
TS28: corpus striatum Ambiguous Regionally restricted Expression was very low or undetectable in the striatum and the ventricular zone/subventricular zone.
TS28: rostral migratory stream Ambiguous Regionally restricted Expression was very low or undetectable in the rostral migratory stream.

Specimen 6M: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Trace 6M
TS28: cerebral cortex Trace Regionally restricted 6M Expression was very weak in the cortical plate.

Specimen 6N: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Trace 6N
TS28: hippocampus Trace 6N
TS28: cerebral cortex Trace Regionally restricted 6N Expression was very weak in the cortical plate.

Specimen 6O: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: brain Trace 6O

Specimen 7E: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum internal granule cell layer Weak 7E
TS28: dentate gyrus Weak 7E
TS28: main olfactory bulb glomerular layer Weak 7E
TS28: main olfactory bulb granule cell layer Weak 7E


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory