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Gene Expression Data
Assay Details
Assay
Reference: J:106092 Tissir F, et al., Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci. 2006 Feb;23(3):597-607
Assay type: RNA in situ
MGI Accession ID: MGI:4946664
Gene symbol: Dvl2
Gene name: dishevelled segment polarity protein 2
Probe: Dvl2 cDNA1
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 1D Expression was present almost equally in neural and non-neural organs.

Specimen 2J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nervous system Strong 2J Expression was maximal in neural tissue and retina.
TS20: retina Strong 2J Expression was maximal in neural tissue and retina.
TS20: skin Strong 2J

Specimen 2K & 2L: embryonic day 12.5 (more )
Note: Fig. 2L is a higher magnification image of the boxed region if Fig. 2K.
Structure Level Pattern Image Note
TS20: brain Present Non-Uniform 2L , 2K Expression was strong in the ventricular zone and low to moderate intensity in postmitotic differentiation fields.
TS20: brain ventricular layer Strong 2L , 2K

Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo mesenchyme Moderate Regionally restricted 3D Expression was detected in connective tissue.
TS22: liver Trace 3D
TS22: brain Weak Regionally restricted 3D Expression was weak except in the ventricular zone.
TS22: brain ventricular layer Present 3D

Specimen Table 2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: brainstem Ambiguous Regionally restricted Expression was very low or undetectable in the reticular formation and the cochleovestibular nuclei.
TS25: cerebellum Present Regionally restricted Expression was present in the external granule layer.
TS25: diencephalon ventricular layer Present
TS25: midbrain ventricular layer Present
TS25: hypothalamus Ambiguous Expression was very low or undetectable.
TS25: midbrain tegmentum Ambiguous Expression was very low or undetectable.
TS25: tectum Ambiguous Expression was very low or undetectable.
TS25: thalamus Ambiguous Expression was very low or undetectable in the dorsal and ventral thalamus.
TS25: retina Present Expression was detected in the ventricular zone and ganglion cells of the retina.
TS25: cortical plate Present Non-Uniform Expression was detected in the cortical plate ventricular zone/subventricular zone and in the cortical plate proper.
TS25: corpus striatum Present Regionally restricted Expression was detected in the striatum ventricular zone/subventricular zone and was very low or undetectable in the striatum.
TS25: main olfactory bulb Present Expression was detected in the olfactory bulb and the mitral cells.

Specimen 4D1: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Strong 4D1
TS25: cerebellum Strong Regionally restricted 4D1 Expression was detected in the external granule layer.

Specimen 4D2: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Strong 4D2

Specimen 4D3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Strong 4D3

Specimen 4D4: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: retina Present Regionally restricted 4D4 Expression was detected in the ventricular zone.
TS25: tooth Present Regionally restricted 4D4 Expression was detected in tooth caps.
TS25: skin Present 4D4

Specimen 5G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: brain Present Non-Uniform 5G Expression was stronger in ventricular zone than in post-migratory neurons.
TS27: brain ventricular layer Present 5G
TS27: rostral migratory stream Present 5G Expression was prominent in the rostral migratory stream.

Specimen Table 3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong
TS28: diencephalon Ambiguous Regionally restricted Expression was very low or undetectable in the diencephalon ventricular zone.
TS28: dorsal thalamus Ambiguous Expression was very low or undetectable.
TS28: hypothalamus Ambiguous Expression was very low or undetectable.
TS28: prethalamus Ambiguous Expression was very low or undetectable.
TS28: cerebral cortex Present Regionally restricted Expression was detected in the cortical plate proper but was very low or undetectable in the cortical plate ventricular zone/subventricular zone.
TS28: corpus striatum Ambiguous Regionally restricted Expression was very low or undetectable in the striatum and the ventricular zone/subventricular zone.
TS28: rostral migratory stream Present
TS28: dentate gyrus Present
TS28: hippocampus pyramidal cell layer Present
TS28: main olfactory bulb granule cell layer Present
TS28: main olfactory bulb mitral cell layer Present

Specimen 6J: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong 6J
TS28: cerebral cortex Moderate Regionally restricted 6J Expression was moderate in the outer cortical ribbon.

Specimen 6K: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Moderate 6K
TS28: hippocampus pyramidal cell layer Moderate 6K

Specimen 6L: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: rostral migratory stream Moderate 6L Expression was moderate in the rostral migratory stream.

Specimen 7D: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Weak 7D


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory