Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grhl2m1Nisw
Name:	grainyhead like transcription factor 2; mutation 1, Lee Niswander
MGI ID:	MGI:4942413
Synonyms:	Grhl21Nisw
Gene:	Grhl2  Location: Chr15:37233280-37363813 bp, + strand  Genetic Position: Chr15, 14.84 cM, cytoband C
Alliance:	Grhl2m1Nisw page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU induced a T to A transversion at position 37,200,529 on chromosome 15 that results in the production of a premature stop codon. The predicted product contains 52 amino acids compared with the full length 625 amino acids. (J:169829)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

12 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grhl2 Mutation:	41 strains or lines available

Original:	J:169829 Pyrgaki C, et al., Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol. 2011 May 1;353(1):38-49
All:	3 reference(s)