Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(NPEPPS)1Skar
Name:	transgene insertion 1, Stanislav Karsten
MGI ID:	MGI:4942404
Synonyms:	hPSA
Transgene:	Tg(NPEPPS)1Skar  Location: unknown
Alliance:	Tg(NPEPPS)1Skar page

Strain of Origin:

FVB/NTac

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(NPEPPS)1Skar expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human NPEPPS (9520) Npepps  (MGI:1101358)   Mutation details: Bacterial artificial chromosome (BAC) library was used to obtain a BAC (#RP11-592D23) containing the entire human aminopeptidase puromycin sensitive (hPSA or NPEPPS) gene. (J:169828)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:169828 Kudo LC, et al., Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice. Hum Mol Genet. 2011 May 1;20(9):1820-33
All:	1 reference(s)