Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(LRRK2*G2019S)1Cjli
Name:	transgene insertion 1, Chenjian Li
MGI ID:	MGI:4942189
Synonyms:	G/S LRRK2
Transgene:	Tg(LRRK2*G2019S)1Cjli  Location: unknown
Alliance:	Tg(LRRK2*G2019S)1Cjli page

Strain of Origin:

FVB/NTac

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(LRRK2*G2019S)1Cjli expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human LRRK2 (120892) Lrrk2  (MGI:1913975)   Mutation details: A 188 Kb bacterial artificial chromosome (BAC) containing the entire human LRRK2 (leucine-rich repeat kinase 2) gene was modified by targeted mutation of the LRRK2 locus to harbor the LRRK2 G2019S mutation associated with autosomal dominant, late-onset Parkinson's disease. (J:169825)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:169825 Li C, A new transgenic mouse expressing mutant human LRRK2 (G2019S), a model for Parkinson's disease. MGI Direct Data Submission. 2011;
All:	10 reference(s)