Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacna2d3tm1Pngr
Name:	calcium channel, voltage-dependent, alpha2/delta subunit 3; targeted mutation 1, Josef M Penninger
MGI ID:	MGI:4887240
Gene:	Cacna2d3  Location: Chr14:28626900-29443821 bp, - strand  Genetic Position: Chr14, 16.8 cM, cytoband B
Alliance:	Cacna2d3tm1Pngr page

Germline Transmission:	Earliest citation of germline transmission: J:167904
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A targeting vector, containing a lacZ gene cassette, was inserted into exon 15 via homologous recombination. Western blot analysis confirmed the absence of protein expression in brains from homozygous mice. (J:167904)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna2d3 Mutation:	64 strains or lines available

Original:	J:167904 Neely GG, et al., A genome-wide Drosophila screen for heat nociception identifies alpha2delta3 as an evolutionarily conserved pain gene. Cell. 2010 Nov 12;143(4):628-38
All:	2 reference(s)