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Gene Expression Data
Assay Details
Assay
Reference: J:143700 Biben C, et al., Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech Dev. 1998 Apr;73(1):125-7
Assay type: RNA in situ
MGI Accession ID: MGI:4882076
Gene symbol: Nkx2-6
Gene name: NK2 homeobox 6
Probe: Nkx2-6 probe1
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 1A Expression is in the endoderm of the lateral walls and lip of the forming foregut pocket.
TS12: embryo endoderm Present Regionally restricted 1A Expression is directly juxtaposed to cardiogenic mesoderm.
Specimen 1B: embryonic day 8.3 (more )
Structure Level Pattern Image Note
TS12: foregut diverticulum Present Regionally restricted 1B Expression is in the forming pharynx in the lateral aspects where pouches will form and is weak at the midline.
Specimen 1C left: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: branchial pouch Present Regionally restricted 1C left Expression is in the ventrolateral endoderm.
TS14: branchial arch ectoderm Present Regionally restricted 1C left Expression is directly adjacent to expressing branchial pouch endoderm.
TS14: branchial arch mesenchyme Present Regionally restricted 1C left Expression is directly adjacent to expressing branchial pouch endoderm.
Specimen 1C right: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: branchial pouch Present Regionally restricted 1C right Expression is in the ventrolateral endoderm.
TS16: branchial arch ectoderm Weak Regionally restricted 1C right Expression is directly adjacent to expressing branchial pouch endoderm.
TS16: branchial arch mesenchyme Weak Regionally restricted 1C right Expression is directly adjacent to expressing branchial pouch endoderm.
Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial pouch Present Regionally restricted 1D Expression is in the ventrolateral endoderm.
TS17: branchial arch ectoderm Present Regionally restricted 1D Expression is directly adjacent to expressing branchial pouch endoderm.
TS17: branchial arch mesenchyme Present Regionally restricted 1D Expression is directly adjacent to expressing branchial pouch endoderm.
Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial pouch Present Regionally restricted 1E Expression is in the ventrolateral endoderm.
TS17: branchial arch ectoderm Weak Regionally restricted 1E Expression is directly adjacent to expressing branchial pouch endoderm.
TS17: branchial arch mesenchyme Weak Regionally restricted 1E Expression is directly adjacent to expressing branchial pouch endoderm.
Specimen 1F: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: outflow tract Present Regionally restricted 1F
Specimen 1G: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS19: foregut-midgut junction Present Regionally restricted 1G Expression is in a short segment spanning ductal connections to the liver and pancreas.
Specimen 2A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 2A Expression is in the endoderm of the lateral walls and lip of the forming foregut pocket.
TS12: embryo endoderm Present Regionally restricted 2A Expression is directly juxtaposed to cardiogenic mesoderm.
Specimen 2B: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 2B Expression is in the endoderm of the lateral walls and lip of the forming foregut pocket.
TS12: embryo endoderm Present Regionally restricted 2B Expression is directly juxtaposed to cardiogenic mesoderm.
Specimen 2C,D: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: foregut diverticulum endoderm Present Regionally restricted 2C , 2D Expression is in the endoderm of the lateral walls and lip of the forming foregut pocket.
TS12: embryo endoderm Present Regionally restricted 2D Expression is directly juxtaposed to cardiogenic mesoderm.
TS12: heart Present Regionally restricted 2C , 2D Expression is in the caudal heart progenitors, concentrated at the cardiac and pericardial junction.
Specimen 2E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: sinus venosus Present 2E
TS13: heart Present Regionally restricted 2E Expression is in the dorsal pericardium.
Specimen 2F: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: branchial pouch Present Regionally restricted 2F Expression is in the ventrolateral endoderm.
TS14: branchial arch ectoderm Present Regionally restricted 2F Expression is directly adjacent to expressing branchial pouch endoderm.
TS14: branchial arch mesenchyme Present Regionally restricted 2F Expression is directly adjacent to expressing branchial pouch endoderm.
TS14: heart Present Regionally restricted 2F Expression is in the dorsal pericardium.
Specimen 2G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial pouch Present Regionally restricted 2G Expression is in the ventrolateral endoderm.
TS15: branchial arch ectoderm Present Regionally restricted 2G Expression is directly adjacent to expressing branchial pouch endoderm.
TS15: branchial arch mesenchyme Present Regionally restricted 2G Expression is directly adjacent to expressing branchial pouch endoderm.
Specimen 2H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: foregut-midgut junction Present Regionally restricted 2H Expression is in a short segment spanning ductal connections to the liver and pancreas.
Specimen 2I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: hindgut Present Regionally restricted 2I Expression is ventral.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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