Aiptm2.1Bra
Targeted Allele Detail
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| Symbol: |
Aiptm2.1Bra |
| Name: |
aryl-hydrocarbon receptor-interacting protein; targeted mutation 2.1, Christopher A Bradfield |
| MGI ID: |
MGI:4867825 |
| Synonyms: |
Aipfx |
| Gene: |
Aip Location: Chr19:4164446-4175858 bp, - strand Genetic Position: Chr19, 3.82 cM
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| Alliance: |
Aiptm2.1Bra page
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Ahrb-1/Ahrb-1 Aiptm2.1Bra/Aiptm2.1Bra Speer6-ps1Tg(Alb-cre)21Mgn/0 mice are resistant to dioxin-induced hepatic damage
Show the 2 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:141575
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette leaving exons 3 through 6 floxed. This allele was used to generate Aiptm1Bra.
(J:141575)
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Generation of the Aiptm2.1Bra allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Aip Mutation: |
26 strains or lines available
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| Original: |
J:141575 Lin BC, et al., Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality. J Biol Chem. 2007 Dec 7;282(49):35924-32 |
| All: |
2 reference(s) |
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Analysis Tools
