Gene Expression Data
Assay Details
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Assay
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Reference:
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J:66508
Sakai R, et al., The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons. Neuron. 2000 Dec;28(3):819-33
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:4867075
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Gene symbol:
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Shc3
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Gene name:
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src homology 2 domain-containing transforming protein C3
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
5O:
postnatal adult; Shc3tm1Paw/Shc3 +
(more  )
Note: Double labeled: blue - Shc3 reporter; brown - Ntrk1 (assay MGI:4867065).
Specimen
5O:
(close  )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: blue - Shc3 reporter; brown - Ntrk1 (assay MGI:4867065).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
Present |
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5O
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Expression only colocalized with ~15% of TrkA+ neurons. The expression pattern appeared mosaic.
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Specimen
5P:
postnatal adult; Shc3tm1Paw/Shc3 +
(more )
Note: Double labeled: blue - Shc3 reporter; brown - Ntrk1 (assay MGI:4867065).
Specimen
5P:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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Double labeled: blue - Shc3 reporter; brown - Ntrk1 (assay MGI:4867065).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dorsal root ganglion |
Present |
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5P
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Expression only colocalized with ~15% of TrkA+ neurons. The expression pattern appeared mosaic.
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Specimen
5Q:
postnatal adult; Shc3tm1Paw/Shc3 +
(more )
Specimen
5Q:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
5R:
postnatal adult; Shc3tm1Paw/Shc3 +
(more )
Specimen
5R:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
7A:
embryonic day 10.5; Shc3tm1Paw/Shc3 +
(more )
Specimen
7A:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: migrating neural crest |
Strong |
Regionally restricted |
7A
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Expression was strong in migrating neural crest cells.
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Specimen
7B:
postnatal day 56; Shc3tm1Paw/Shc3 +
(more )
Specimen
7B:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal day 56
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: superior cervical ganglion |
Present |
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7B
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Expression was detected in a high percentage of superior cervical ganglion neurons.
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Specimen
7C:
postnatal day 56; Shc3tm1Paw/Shc3 +
(more )
Specimen
7C:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Shc3tm1Paw/Shc3+
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Age:
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postnatal day 56
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: superior cervical ganglion |
Present |
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7C
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Expression was detected in a high percentage of superior cervical ganglion neurons.
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Analysis Tools