Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(CLEC4C-HBEGF)956Cln
Name:	transgene insertion 956, Marco Colonna
MGI ID:	MGI:4847575
Synonyms:	BDCA2-DTR Tg, Tg(CLEC4C-DTR)956Cln
Transgene:	Tg(CLEC4C-HBEGF)956Cln  Location: unknown
Alliance:	Tg(CLEC4C-HBEGF)956Cln page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(CLEC4C-HBEGF)956Cln expresses 1 gene Transgene expresses: Organism Expressed Gene Note monkey HBEGF   Mutation details: This transgene was designed with a simian diphtheria toxin receptor (DTR; HBEGF) under the transcriptional control of a human promoter, a simian virus 40 (SV40) intervening sequence, and SV40 polyadenylation site. Line 956 was generated. (J:166504)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:166504 Swiecki M, et al., Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual. Immunity. 2010 Dec 14;33(6):955-66
All:	36 reference(s)