Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tfpitm1.1Rdsi
Name:	tissue factor pathway inhibitor; targeted mutation 1.1, Robert D Simari
MGI ID:	MGI:4836740
Gene:	Tfpi  Location: Chr2:84263199-84307119 bp, - strand  Genetic Position: Chr2, 49.41 cM
Alliance:	Tfpitm1.1Rdsi page

Germline Transmission:	Earliest citation of germline transmission: J:164530
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A FRT flanked Neomycin cassette was inserted within intron 3 and exon 4 was floxed by homologous recombination. The selection cassette was removed by flp mediated recombination. (J:164530)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tfpi Mutation:	45 strains or lines available

Original:	J:164530 White TA, et al., Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis. Blood. 2010 Sep 9;116(10):1787-94
All:	3 reference(s)