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Stat1tm1Mam
Targeted Allele Detail
Summary
Symbol: Stat1tm1Mam
Name: signal transducer and activator of transcription 1; targeted mutation 1, Lothar Hennighausen
MGI ID: MGI:4821871
Synonyms: Stat1 fl/fl
Gene: Stat1  Location: Chr1:52158599-52201024 bp, + strand  Genetic Position: Chr1, 26.81 cM
Alliance: Stat1tm1Mam page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163376
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to place a loxP flanked neomycin resistance gene upstream of the first untranslated exon followed by a loxP site downstream of the first translated exon. The neo cassette was removed by germ-line cre-mediated resombination leaving loxP sites flanking the first two untranslated exons and the first translated exon. (J:163376)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Stat1 Mutation:  72 strains or lines available
References
Original:  J:163376 Klover P, et al., Generation of a Stat1 conditional allele. MGI Direct Data Submission. 2010;
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory