About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stat1tm1Mam
targeted mutation 1, Lothar Hennighausen
MGI:4821871
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Stat1tm1Mam/Stat1tm1Mam
Tg(Wap-cre)11738Mam/0 		involves: 129S/SvEv * C57BL/6 * SJL MGI:4942395
cn2
 		Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-Erbb2*,-cre)1Mul/0 		involves: 129S/SvEv * FVB MGI:4821942
cn3
 		Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-cre)#Mam/0 		involves: 129S/SvEv * FVB MGI:4942394


Genotype
MGI:4942395
cn1
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(Wap-cre)11738Mam/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (72 available)
Tg(Wap-cre)11738Mam mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:169262 )
N
• female mice exhibit normal mammary gland architecture




Genotype
MGI:4821942
cn2
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-Erbb2*,-cre)1Mul/0
Genetic
Background		 involves: 129S/SvEv * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (72 available)
Tg(MMTV-Erbb2*,-cre)1Mul mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased tumor latency ( J:169262 )
• median time to tumor onset is 49 weeks compared with 62 weeks for Tg(MMTV-Erbb2*,-cre)1Mul mice




Genotype
MGI:4942394
cn3
Allelic
Composition		 Stat1tm1Mam/Stat1tm1Mam
Tg(MMTV-cre)#Mam/0
Genetic
Background		 involves: 129S/SvEv * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Mam mutation (1 available); any Stat1 mutation (72 available)
Tg(MMTV-cre)#Mam mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:169262 )
N
• female mice exhibit normal lactation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory