Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Dbh-cre/ERT2)198.1Hroh
Name:	transgene insertion 198.1, Hermann Rohrer
MGI ID:	MGI:4821735
Synonyms:	DBHCreERT2, DBH-CT198.1
Transgene:	Tg(Dbh-cre/ERT2)198.1Hroh  Location: unknown
Alliance:	Tg(Dbh-cre/ERT2)198.1Hroh page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Dbh-cre/ERT2)198.1Hroh expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Dbh (MGI:94864)   Mutation details: A cre-ERT2 cassette with a polyA sequence was inserted into a BAC containing the mouse Dbh gene by homologous recombination, resulting in cre expression directed by the Dbh promoter. This construct was integrated into the C57BL/6 background. Cre induction by tamoxifen in mice crossed to a reporter line exhibited cre activity in noradrenergic cells (sympathetic ganglia, adrenal chromaffin cells, and the locus ceruleus). (J:163233, J:180731)

Generation of Tg(Dbh-cre/ERT2)198.1Hroh.

Activity:	Tissue activity of this recombinase allele
Driver:	Dbh (mouse) Summary of all recombinase alleles driven by Dbh. Comparative matrix view of recombinase activities Alliance mouse Dbh gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:163233 Tsarovina K, et al., The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons. J Neurosci. 2010 Aug 11;30(32):10833-43
All:	6 reference(s)