Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kidins220tm1.1Mvc
Name:	kinase D-interacting substrate 220; targeted mutation 1.1, Moses V Chao
MGI ID:	MGI:4820793
Gene:	Kidins220  Location: Chr12:25024924-25113151 bp, + strand  Genetic Position: Chr12, 8.54 cM
Alliance:	Kidins220tm1.1Mvc page

Germline Transmission:	Earliest citation of germline transmission: J:162839
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 14 and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of exon 14. Cre mediated recombination removed exon 14 and the neo cassette. (J:162839)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kidins220 Mutation:	79 strains or lines available

Original:	J:162839 Wu SH, et al., Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. Dev Neurobiol. 2009 Aug;69(9):547-57
All:	4 reference(s)