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Gene Expression Data
Assay Details
Assay
Reference: J:103820 Reiter JF, et al., Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes Dev. 2006 Jan 1;20(1):22-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4462006
Gene symbol: Foxa2
Gene name: forkhead box A2
Antibody: 4C7
Results
Specimen 3B wild type: embryonic day 9.5 (more )
Note: Double labeled: green - Foxa2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube floor plate Present 3B wild type

Specimen 3B Tectonic-/-: embryonic day 9.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Foxa2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube floor plate Absent 3B Tectonic-/-

Specimen 3B Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: Double labeled: green - Foxa2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube Present 3B Ptch-/- Expression in the mutant was expanded compared to wild type.

Specimen 3B Tectonic-/- Ptch-/-: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps, Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Foxa2; red - Pax6 (assay MGI:4461989).
Structure Level Pattern Image Note
TS15: neural tube floor plate Absent 3B Tectonic-/- Ptch-/-

Specimen 3E wild type: embryonic day 10.5 (more )
Note: Double labeled: green - Foxa2; red - Olig2 (assay MGI:4462010).
Structure Level Pattern Image Note
TS17: neural tube floor plate Present 3E wild type

Specimen 3E Tectonic-/-: embryonic day 10.5; Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Foxa2; red - Olig2 (assay MGI:4462010).
Structure Level Pattern Image Note
TS17: neural tube floor plate Absent 3E Tectonic-/-

Specimen 3E Rab23 opb/opb: embryonic day 10.5; Rab23opb2/Rab23opb2 (more )
Note: Double labeled: green - Foxa2; red - Olig2 (assay MGI:4462010).
Structure Level Pattern Image Note
TS17: neural tube Present 3E Rab23 opb/opb Expression in the mutant was expanded compared to wild type.

Specimen 3E Tect-/- Rab23 opb/opb: embryonic day 10.5; Rab23opb2/Rab23opb2, Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg (more )
Note: Double labeled: green - Foxa2; red - Olig2 (assay MGI:4462010).
Structure Level Pattern Image Note
TS17: neural tube floor plate Absent 3E Tect-/- Rab23 opb/opb


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory