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Gene Expression Data
Assay Details
Assay
Reference: J:157819 Shimogori T, et al., A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
Assay type: RNA in situ
MGI Accession ID: MGI:4450778
Gene symbol: Rorb
Gene name: RAR-related orphan receptor beta
Probe: UI-M-CD0-ayn-e-10-0-UI.s1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S7q: embryonic day 11.5 (more )
Note: Double labeled: blue - Rorb; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS19: diencephalon Absent S7_q This annotation was inferred from the data presented in Supp. Table 4.
Specimen S7r: embryonic day 12.5 (more )
Note: Double labeled: blue - Rorb; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS20: diencephalon Absent S7_r This annotation was inferred from the data presented in Supp. Table 4.
Specimen S7s: embryonic day 14.5 (more )
Note: Double labeled: blue - Rorb; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS22: hypothalamus Present Regionally restricted S7_s Expression is present in the developing suprachiasmatic nucleus.
Specimen S7t: embryonic day 16.5 (more )
Note: Double labeled: blue - Rorb; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS24: hypothalamus Present Regionally restricted S7_t Expression is present in the developing suprachiasmatic nucleus.
Specimen Rorb - E11.5: embryonic day 11.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS19: diencephalon lateral wall mantle layer Ambiguous Rorb-Shh E11.5_coronal , Rorb-Shh E11.5_sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
TS19: diencephalon lateral wall ventricular layer Ambiguous Rorb-Shh E11.5_sagittal , Rorb-Shh E11.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
TS19: telencephalon mantle layer Ambiguous Rorb-Shh E11.5_coronal , Rorb-Shh E11.5_sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
TS19: telencephalon ventricular layer Weak Non-Uniform Rorb-Shh E11.5_coronal , Rorb-Shh E11.5_sagittal There is weak staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Rorb - E12.5: embryonic day 12.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS20: cerebral cortex intermediate zone Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS20: cerebral cortex ventricular layer Ambiguous Rorb-Shh E12.5_sagittal , Rorb-Shh E12.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS20: cortical plate Ambiguous Rorb-Shh E12.5_sagittal , Rorb-Shh E12.5_coronal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS20: diencephalon mantle layer Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
TS20: diencephalon ventricular layer Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS20: ganglionic eminence Weak Non-Uniform Rorb-Shh E12.5_sagittal , Rorb-Shh E12.5_coronal There is weak staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
TS20: hypothalamus mantle layer Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS20: hypothalamus ventricular layer Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS20: thalamus mantle layer Ambiguous Rorb-Shh E12.5_sagittal , Rorb-Shh E12.5_coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS20: thalamus ventricular layer Ambiguous Rorb-Shh E12.5_coronal , Rorb-Shh E12.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Rorb - E14.5: embryonic day 14.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS22: cerebral cortex ventricular layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS22: cortical plate Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS22: diencephalon mantle layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
TS22: diencephalon ventricular layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS22: ganglionic eminence Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
TS22: hypothalamus mantle layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS22: hypothalamus ventricular layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS22: thalamus mantle layer Weak Non-Uniform Rorb-Shh E14.5_coronal , Rorb-Shh E14.5_sagittal There is weak staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
TS22: thalamus ventricular layer Ambiguous Rorb-Shh E14.5_sagittal , Rorb-Shh E14.5_coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Rorb - E16.5: embryonic day 16.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Ambiguous Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS24: cerebral cortex ventricular layer Ambiguous Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
TS24: cortical plate Ambiguous Rorb-Shh E16.5_sagittal , Rorb-Shh E16.5_coronal Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS24: diencephalon mantle layer Moderate Non-Uniform Rorb-Shh E16.5_sagittal , Rorb-Shh E16.5_coronal There is moderate staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones.
TS24: diencephalon ventricular layer Ambiguous Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
TS24: ganglionic eminence Ambiguous Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
TS24: hypothalamus mantle layer Moderate Non-Uniform Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal There is moderate staining in the mantle zone of the DAH and weak staining in the ventral POA. Staining is either absent or ubiquitous in the mantle zone of the dorsal POA, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH and the PH.
TS24: hypothalamus ventricular layer Very strong Non-Uniform Rorb-Shh E16.5_sagittal , Rorb-Shh E16.5_coronal There is very strong staining in the VZ of the SCH nucleus and strong staining in the DMH nucleus. Staining is either absent or ubiquitous in the VZ of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the DAH and the PH.
TS24: thalamus mantle layer Moderate Non-Uniform Rorb-Shh E16.5_sagittal , Rorb-Shh E16.5_coronal There is moderate staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
TS24: thalamus ventricular layer Ambiguous Rorb-Shh E16.5_coronal , Rorb-Shh E16.5_sagittal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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