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Sall1tm4.1Ryn
Targeted Allele Detail
Summary
Symbol: Sall1tm4.1Ryn
Name: spalt like transcription factor 1; targeted mutation 4.1, Ryuichi Nishinakamura
MGI ID: MGI:4443121
Synonyms: Sall1flox
Gene: Sall1  Location: Chr8:89753867-89770790 bp, - strand  Genetic Position: Chr8, 43.51 cM, cytoband D
Alliance: Sall1tm4.1Ryn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159449
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upsteam of exon 1 and an additional loxP site inserted downstream of exon 1. Cre mediated recombination removed the neo cassette leaving exon 1 floxed. (J:159449)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sall1 Mutation:  77 strains or lines available
References
Original:  J:159449 Yuri S, et al., Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells. 2009 Apr;27(4):796-805
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory