Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Slc7a11m1Mtka
Name:	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; mutation 1, Masato Tanaka
MGI ID:	MGI:4442905
Synonyms:	xCTmu
Gene:	Slc7a11  Location: Chr3:50319385-50403947 bp, - strand  Genetic Position: Chr3, 21.72 cM, cytoband D
Alliance:	Slc7a11m1Mtka page

Strain of Origin:

C57BL/6

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a G to T transversion in exon 10 that results in a premature termination at position 383 glycine. (J:159323)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc7a11 Mutation:	49 strains or lines available

Original:	J:159323 Nabeyama A, et al., xCT deficiency accelerates chemically induced tumorigenesis. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6436-41
All:	2 reference(s)