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Gene Expression Data
Assay Details
Assay
Reference: J:21265 Dolle P, et al., Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation. Nature. 1989 Dec 14;342(6251):767-72
Assay type: RNA in situ
MGI Accession ID: MGI:4442506
Gene symbol: Hoxd12
Gene name: homeobox D12
Probe: Hox5-6
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen not shown: embryonic day 8.75 (more )
Structure Level Pattern Image Note
TS13: trunk mesenchyme Absent No expression in the forelimb field before limb bud outgrowth.

Specimen 1a left: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS14: forelimb bud mesenchyme Absent 1a left Hox-5.6

Specimen 1a right: embryonic day 9.25 (more )
Structure Level Pattern Image Note
TS14: forelimb bud mesenchyme Absent 1a right Hox-5.6

Specimen 1b: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 1b Hox-5.6 Expression in distal limb mesoderm, only in very posterior planes of section.

Specimen 1c: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 1c Hox-5.6 Expression in distal limb mesoderm, only in very posterior planes of section.

Specimen 1d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb pre-cartilage condensation Present Regionally restricted 1d Hox-5.6 Expression in central limb precartilage condensations restricted to more distal blastemas.

Specimen 1e: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 1e Hox-5.6
TS20: hindlimb mesenchyme Present Regionally restricted 1e Hox-5.6

Specimen 1f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot mesenchyme Present Regionally restricted 1f Hox-5.6 Abundant expression in mesenchymal cells surrounding the phalangeal cartilage anlage.

Specimen not shown: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present
TS15: forelimb bud ectoderm Absent

Specimen 4a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4a Hox-5.6 Expression restricted to posterior mesoderm, as well as to along the ventral side.

Specimen 4b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 4b Hox-5.6
TS20: hindlimb mesenchyme Present Regionally restricted 4b Hox-5.6


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory