Tg(tetO-Klf4)#Jae Transgene Detail MGI Mouse (MGI:4438886)

Tg(tetO-Klf4)#Jae
Transgene Detail

Summary

Symbol:	Tg(tetO-Klf4)#Jae
Name:	transgene insertion #, Rudolf Jaenisch
MGI ID:	MGI:4438886
Transgene:	Tg(tetO-Klf4)#Jae Location: unknown
Alliance:	Tg(tetO-Klf4)#Jae page

Transgene
origin

Germline Transmission:	Earliest citation of germline transmission: J:158492
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Transgene
description

Transgene Type:		Transgenic (Inducible, Inserted expressed sequence)
Inducer:		doxycycline/tetracycline
Mutation:		Insertion
		Mutation details: The tetO promoter was used to drive doxycycline-inducible expression of the mouse cDNA in a lentivirus construct. No line number was given. (J:158493)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

This transgene was originally created in iBiPS #9 cells that contain Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae}, Nanog^tm1Hoch, and 3 other lentivirus constructs in which tetO drives the expression of Sox2, Pou5f1, and c-MYC.

References

Original:	J:158492 Markoulaki S, et al., Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nat Biotechnol. 2009 Feb;27(2):169-71
All:	2 reference(s)

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