Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Myh6-Cast)1Gwd
Name:	transgene insertion 1, Gerald W Dorn II
MGI ID:	MGI:4437429
Synonyms:	CSTN TG
Transgene:	Tg(Myh6-Cast)1Gwd  Location: unknown
Alliance:	Tg(Myh6-Cast)1Gwd page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Myh6-Cast)1Gwd expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Cast (MGI:1098236)   Mutation details: A transgenic vector was generated including the entire coding region of the calpastatin (Cast) gene under control of an alpha-myosin heavy chain (Myh6) promoter. One line was created with expression in the heart. (J:133797)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:133797 Galvez AS, et al., Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis. Circ Res. 2007 Apr 13;100(7):1071-8
All:	1 reference(s)