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Gene Expression Data
Assay Details
Assay
Reference: J:157352 Loftus SK, et al., Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
Assay type: RNA in situ
MGI Accession ID: MGI:4437027
Gene symbol: Mitf
Gene name: melanogenesis associated transcription factor
Probe: Mitf cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3 C57BL/6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate Expression is in melanoblasts.
TS19: eye Present
Specimen 3 Mitf Mi/+: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is reduced.
TS19: eye Present
Specimen 3 Mitf Mi/Mi: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is severely reduced.
TS19: eye Present
TS19: head mesenchyme derived from neural crest Absent Absent in melanoblasts.
TS19: trunk mesenchyme derived from neural crest Absent Absent in melanoblasts.
Specimen 3 Sox10 LacZ/+: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is reduced.
TS19: eye Present
Specimen 3 Sox10 LacZ/LacZ: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate The density of expressing melanoblasts is severely reduced.
TS19: eye Present
TS19: head mesenchyme derived from neural crest Absent Absent in melanoblasts.
TS19: trunk mesenchyme derived from neural crest Absent Absent in melanoblasts.
Specimen 5A Mitf+/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 5_Mitf +/+ Mitf
Specimen 5A Mitf Mi/+: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 5_Mitf Mi/+ Mitf
Specimen 5A Mitf Mi/Mi: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 5_Mitf Mi/Mi Mitf Expression in this mutant is the same as in wild-type embryos.
Specimen sl_Mitf_+_+_10.5a_fore_25: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5a_fore_25 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_10.5a_head_25: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5a_head_25 Expression is in melanoblasts.
TS17: eye Present sl_Mitf_+_+_10.5a_head_25
Specimen sl_Mitf_+_+_10.5a_head_40: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5a_head_40 Expression is in melanoblasts.
TS17: eye Present sl_Mitf_+_+_10.5a_head_40
Specimen sl_Mitf_+_+_10.5a_side_20: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5a_side_20 Expression is in melanoblasts.
TS17: eye Present sl_Mitf_+_+_10.5a_side_20
Specimen sl_Mitf_+_+_10.5a_tail_40: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5a_tail_40 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_10.5b_fore_25: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5b_fore_25 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_10.5b_head_25: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5b_head_25 Expression is in melanoblasts.
TS17: eye Present sl_Mitf_+_+_10.5b_head_25
Specimen sl_Mitf_+_+_10.5b_head_40: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5b_head_40 Expression is in melanoblasts.
TS17: eye Present sl_Mitf_+_+_10.5b_head_40
Specimen sl_Mitf_+_+_10.5b_side_20: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5b_side_20
Specimen sl_Mitf_+_+_10.5b_tail_40: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_10.5b_tail_40 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_a_fore_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_fore_25 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_a_head_40tif: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_head_40tif Expression is in melanoblasts.
TS19: eye Present sl_Mitf_+_+_a_head_40tif
Specimen sl_Mitf_+_+_a_head-25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_head-25 Expression is in melanoblasts.
TS19: eye Present sl_Mitf_+_+_a_head-25
Specimen sl_Mitf_+_+_a_hind_25: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_hind_25 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_a_hind_40: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_hind_40 Expression is in melanoblasts.
Specimen sl_Mitf_+_+_a_side_16-20: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_side_16-20 Expression is in melanoblasts.
TS19: eye Present sl_Mitf_+_+_a_side_16-20
Specimen sl_Mitf_+_+_a_side-16-20a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Mitf_+_+_a_side-16-20a Expression is in melanoblasts.
TS19: eye Present sl_Mitf_+_+_a_side-16-20a
Specimen sl_Mitf_Mi_+_c_fore_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_fore_25 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_Mi_+_c_head_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_head_25 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_Mi_+_c_head_25
Specimen sl_Mitf_Mi_+_c_head_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_head_40 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_Mi_+_c_head_40
Specimen sl_Mitf_Mi_+_c_hind_25: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_hind_25 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_Mi_+_c_hind_40: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_hind_40 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_Mi_+_c_side_16-: embryonic day 11.5; MitfMi/Mitf+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_+_c_side_16- The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_Mi_+_c_side_16-
Specimen sl_Mitf_Mi_Mi_a_head_25: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_Mi_Mi_a_head_25 Absent in melanoblasts.
TS19: eye Present sl_Mitf_Mi_Mi_a_head_25
Specimen sl_Mitf_Mi_Mi_a_head_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_Mi_Mi_a_head_40 Absent in melanoblasts.
TS19: eye Present sl_Mitf_Mi_Mi_a_head_40
Specimen sl_Mitf_Mi_Mi_a_tail_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_Mi_a_tail_40 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_Mi_Mi_b_head_25: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_Mi_Mi_b_head_25 Absent in melanoblasts.
TS19: eye Present sl_Mitf_Mi_Mi_b_head_25
Specimen sl_Mitf_Mi_Mi_b_head_40: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_Mi_Mi_b_head_40 Absent in melanoblasts.
TS19: eye Present sl_Mitf_Mi_Mi_b_head_40
Specimen sl_Mitf_Mi_Mi_b_side_16: embryonic day 11.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_Mi_Mi_b_side_16 The density of expressing melanoblasts in the tail is reduced.
TS19: eye Present sl_Mitf_Mi_Mi_b_side_16
Specimen sl_Mitf_S10_+_a_fore_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_fore_25 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_S10_+_a_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_head_25 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_S10_+_a_head_25
Specimen sl_Mitf_S10_+_a_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_head_40 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_S10_+_a_head_40
Specimen sl_Mitf_S10_+_a_hind_25: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_hind_25 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_S10_+_a_hind_40: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_hind_40 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_S10_+_a_side_16-20: embryonic day 11.5; Sox10tm1Weg/Sox10+ (more )
Structure Level Pattern Image Note
TS19: mesenchyme derived from neural crest Present Punctate sl_Mitf_S10_+_a_side_16-20 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_S10_+_a_side_16-20
Specimen sl_Mitf_s10_s10_a_fore_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_fore_25
TS19: eye Present sl_Mitf_s10_s10_a_fore_25
Specimen sl_Mitf_s10_s10_a_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_head_25
TS19: eye Present sl_Mitf_s10_s10_a_head_25
Specimen sl_Mitf_s10_s10_a_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_head_40
TS19: eye Present sl_Mitf_s10_s10_a_head_40
Specimen sl_Mitf_s10_s10_a_hind_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_hind_25
Specimen sl_Mitf_s10_s10_a_hind_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_hind_40
Specimen sl_Mitf_s10_s10_a_side_16-2: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_side_16-2
TS19: trunk mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_a_side_16-2
TS19: eye Present sl_Mitf_s10_s10_a_side_16-2
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_s10_s10_a_side_16-2 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_s10_s10_a_tail_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_s10_s10_a_tail_40 The density of expressing melanoblasts is reduced.
Specimen sl_Mitf_s10_s10_b_head_25: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_b_head_25
TS19: eye Present sl_Mitf_s10_s10_b_head_25
Specimen sl_Mitf_s10_s10_b_head_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_b_head_40
TS19: eye Present sl_Mitf_s10_s10_b_head_40
Specimen sl_Mitf_s10_s10_b_side_16-2: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_b_side_16-2
TS19: trunk mesenchyme derived from neural crest Absent sl_Mitf_s10_s10_b_side_16-2
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_s10_s10_b_side_16-2 The density of expressing melanoblasts is reduced.
TS19: eye Present sl_Mitf_s10_s10_b_side_16-2
Specimen sl_Mitf_s10_s10_b_tail_40: embryonic day 11.5; Sox10tm1Weg/Sox10tm1Weg (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Punctate sl_Mitf_s10_s10_b_tail_40 The density of expressing melanoblasts is reduced.
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03/25/2025
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