Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Emu-TXLNA)1Amjr
Name:	transgene insertion 1, Julian Ambrus Jr
MGI ID:	MGI:4430747
Synonyms:	IL-14alpha Tg, pEuSR-IL-14alpha
Transgene:	Tg(Emu-TXLNA)1Amjr  Location: unknown  Genetic Position: Chr18, Syntenic
Alliance:	Tg(Emu-TXLNA)1Amjr page

Strain of Origin:

(C3H x C57BL/6J)F1

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(Emu-TXLNA)1Amjr expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human TXLNA (200081) Txlna  (MGI:105968)   Mutation details: The pEmuSR-IL-14alpha transgene was designed with the Emu immunoglobulin heavy chain enhancer/SV40 promoter regions (from the pEmuSR vector) upstream of a hemagglutinin-tagged human IL-14alpha (TXLNA or taxilin alpha) cDNA sequence (human IL-14alpha is a cytokine encoded by the plus strand of the IL-14 gene using exons 3-10). FISH analysis showed positive immunofluorescence on chromosome 18. (J:117018)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:117018 Shen L, et al., Development of autoimmunity in IL-14alpha-transgenic mice. J Immunol. 2006 Oct 15;177(8):5676-86
All:	5 reference(s)