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Tg(CAG-cre/Esr1*)1Egwa
Transgene Detail
Summary
Symbol: Tg(CAG-cre/Esr1*)1Egwa
Name: transgene insertion 1, Gyohei Egawa
MGI ID: MGI:4430073
Synonyms: CAG-MerCreMer, CAG-MerCreMer Tg, Tg(CAG-cre/Esr1)1Egwa
Transgene: Tg(CAG-cre/Esr1*)1Egwa  Location: unknown  
Alliance: Tg(CAG-cre/Esr1*)1Egwa page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(CAG-cre/Esr1*)1Egwa expression driven by 1 gene
 
Mutation detailsA transgenic construct encoding cre recombinase with mutated estrogen receptor ligand-binding domains (Esr1, Mer) at the N- and C-termini (MerCreMer) under control of the CAG promoter was injected into B6DF1 fertilized eggs to generate CAG-MerCreMer mice. (J:157054)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: CAG (chicken)
Summary of all recombinase alleles driven by CAG.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:157054 Egawa G, et al., Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol. 2009 Oct;129(10):2386-95
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory