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Gene Expression Data
Assay Details
Assay
Reference: J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
Assay type: RNA in situ
MGI Accession ID: MGI:4429950
Gene symbol: Zbtb18
Gene name: zinc finger and BTB domain containing 18
Probe: Zfp238 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Table 1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Strong Expression is present in the muscle-forming region.

Specimen S2: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: limb mesenchyme Absent S2_RP58 E9.5

Specimen S2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Absent S2_RP58 E10.5

Specimen S2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present S2_RP58 E11.5 Expression is present within the muscle-forming tissues in the limb middle mesenchyme.

Specimen 2: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: limb Absent 2A RP58 E9.5
TS15: neural tube Present 2A RP58 E9.5

Specimen 2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb Absent 2A RP58 E10.5 whole mount
TS17: neural tube Present 2A RP58 E10.5 whole mount

Specimen 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Moderate 2A RP58 E11.5 whole mount Expression appears to be occuring during myogenesis.

Specimen 2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present 2A RP58 E10.5 section
TS17: forelimb bud mesenchyme Absent 2A RP58 E10.5 section

Specimen 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 2A RP58 E11.5 section

Specimen S3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present S3_Pax3+/+ Expression is present in the muscle.

Specimen S3: embryonic day 11.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Absent S3_Pax3Sp/Sp Muscle tissues do not form in the limb buds of the mutants.

Specimen S6 left: embryonic day 11.5; Myogtm1Yin/Myog+ (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present S6_Myog+/- Expression is present in the muscle.
TS19: myotome Present S6_Myog+/-

Specimen S6 center: embryonic day 11.5; Myogtm1Yin/Myogtm1Yin (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present S6_Myog-/- whole mount As in wild type, expression is present in the muscle.
TS19: myotome Present S6_Myog-/- whole mount

Specimen S6 right: embryonic day 11.5; Myogtm1Yin/Myogtm1Yin (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present S6_Myog-/- section As in wild type, expression is present in the muscle.
TS19: myotome Present S6_Myog-/- section

Specimen S8 upper: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present S8_RP58 E12.5 upper Expression is present in muscle regions.

Specimen S8 upper: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb musculature Present S8_RP58 E13.5 upper Expression is present in muscle regions.

Specimen S8 lower: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present S8_RP58 E12.5 lower Expression is present in muscle regions.

Specimen S8 lower: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb musculature Present S8_RP58 E13.5 lower Expression is present in muscle regions.

Specimen Table S4 - E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trunk somite Strong
TS15: tail Strong
TS15: future hindbrain Strong Staining is present in the metencephalon.
TS15: neural tube Strong There is strong staining in the medial and lateral neural tube.
TS15: dorsal root ganglion Moderate

Specimen Table S4 - E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Strong Non-Uniform Staining is strong in the middle and proximal limb and moderate in the progress zone.
TS17: trunk somite Strong
TS17: tail Strong
TS17: 1st branchial arch maxillary component Strong Staining is present in the maxillary process.
TS17: eye Moderate
TS17: hindbrain Strong Staining is present in the metencephalon.
TS17: neural tube Strong There is strong staining in the medial and lateral neural tube.
TS17: dorsal root ganglion Strong

Specimen Table S4 - E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Strong Regionally restricted Staining is present in the middle limb and muscle.
TS19: trunk somite Strong
TS19: tail Strong
TS19: maxillary process Strong Staining is present in the maxillary process.
TS19: eye Moderate
TS19: midbrain Moderate
TS19: hindbrain Strong Staining is present in the metencephalon.
TS19: neural tube Strong Non-Uniform Staining is strong in the medial neural tube and moderate in the lateral neural tube.
TS19: dorsal root ganglion Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory