Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stk4tm1Dlim
Name:	serine/threonine kinase 4; targeted mutation 1, Dae-Sik Lim
MGI ID:	MGI:4414818
Synonyms:	Mst1-
Gene:	Stk4  Location: Chr2:163916033-163997444 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance:	Stk4tm1Dlim page

Germline Transmission:	Earliest citation of germline transmission: J:155001
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 3.3 kb genomic fragment including exons 3 and 4 was replaced with a pgk-puro resistance cassette via homologous recombination. Western blot and RT-PCR analysis confirmed the absence of expression in homozygous MEFs. (J:155001)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:	72 strains or lines available

Original:	J:155001 Oh S, et al., Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol. 2009 Dec;29(23):6309-20
All:	13 reference(s)