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Gene Expression Data
Assay Details
Assay
Reference: J:153561 Dominguez-Frutos E, et al., Tissue-specific requirements for FGF8 during early inner ear development. Mech Dev. 2009 Oct;126(10):873-81
Assay type: RNA in situ
MGI Accession ID: MGI:4366544
Gene symbol: Neurod1
Gene name: neurogenic differentiation 1
Probe: neuroD probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S3A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: otocyst Present Regionally restricted S3A Expression in the neurogenic region of the otic vesicle.
TS16: facio-acoustic ganglion complex Present Regionally restricted S3A Expression in in neuronal precursors corresponding to the trigeminal (V), facial (VII), otic (VII), glossopharyngeal (IX) and vagal (X) ganglia.
TS16: glossopharyngeal ganglion Present S3A Expression in in neuronal precursors corresponding to the trigeminal (V), facial (VII), otic (VII), glossopharyngeal (IX) and vagal (X) ganglia.
TS16: trigeminal ganglion Present S3A Expression in in neuronal precursors corresponding to the trigeminal (V), facial (VII), otic (VII), glossopharyngeal (IX) and vagal (X) ganglia.
TS16: vagus ganglion Present S3A Expression in in neuronal precursors corresponding to the trigeminal (V), facial (VII), otic (VII), glossopharyngeal (IX) and vagal (X) ganglia.
Specimen S3B: embryonic day 10.0; Fgf3tm1Sng/Fgf3tm1Sng, Fgf8tm1.3Mrt/Fgf8tm1.4Mrt, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: otocyst Absent S3B Expression was absent in the neurogenic region of the otic vesicle.
TS16: glossopharyngeal ganglion Present S3B
TS16: trigeminal ganglion Present S3B
TS16: vagus ganglion Present S3B
TS16: facio-acoustic ganglion complex Present S3B Reduced labelling was noted in the facial ganglion in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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