Tg(Myh6-SOD2,Tyr)3Pne
Transgene Detail
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| Symbol: |
Tg(Myh6-SOD2,Tyr)3Pne |
| Name: |
transgene insertion 3, Paul N Epstein |
| MGI ID: |
MGI:4360100 |
| Synonyms: |
MnSOD3, MS, MySOD |
| Transgene: |
Tg(Myh6-SOD2,Tyr)3Pne Location: unknown
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| Alliance: |
Tg(Myh6-SOD2,Tyr)3Pne page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Myh6-SOD2,Tyr)3Pne expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
SOD2 (6648) |
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Mutation details: A transgenic construct containing the human, superoxide dismutase 2, mitochondrial gene under the control of the mouse myosin, heavy polypeptide 6, cardiac muscle, alpha, promoter and a polyadenylation sequence (550-bp fragment of the rat insulin II gene) was co-injected with a tyrosinase minigene where tyrosinase is under the control of the tyrosinase promoter, commonly referred to as TyBs into fertilized FVB mouse eggs. Founder line 3 was subsequently established.
(J:106815, J:152215)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:106815 Mantena SK, et al., Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumors. J Nutr. 2005 Dec;135(12):2871-7 |
| All: |
5 reference(s) |
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Analysis Tools
