Tg(CD2-Ccdc86)1Hfuj
Transgene Detail
|
|
| Symbol: |
Tg(CD2-Ccdc86)1Hfuj |
| Name: |
transgene insertion 1, Hodaka Fujii |
| MGI ID: |
MGI:4356279 |
| Synonyms: |
Cyclon-Tg, HA-Cyclon |
| Transgene: |
Tg(CD2-Ccdc86)1Hfuj Location: unknown
|
| Alliance: |
Tg(CD2-Ccdc86)1Hfuj page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(CD2-Ccdc86)1Hfuj expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Ccdc86 (MGI:1277220) |
|
|
| |
|
Tg(CD2-Ccdc86)1Hfuj expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
CD2 (914) |
|
|
|
| |
|
Mutation details: Murine Ccdc86 coding sequence was inserted into the VA-hCD2 expression vector and the resulting transgene was injected into the pronuclei of fertilized eggs. mRNA and protein expression was confirmed by RT-PCR and immunoblot analysis of splenocytes. Expression level of the transgene product was 1.7 and 1.49 fold greater than endogenous protein in CD4+ or CD8+ T cells. The n-terminus of the protein product is tagged by an HA epitope tag.
(J:151722)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:151722 Saint Fleur S, et al., Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon. Blood. 2009 Aug 13;114(7):1355-65 |
| All: |
1 reference(s) |
|
Analysis Tools
