About   Help   FAQ
Tg(En2-lacZ)1Alj
Transgene Detail
Summary
Symbol: Tg(En2-lacZ)1Alj
Name: transgene insertion 1, Alexandra L Joyner
MGI ID: MGI:4355552
Synonyms: CCS-lacZ, MC4
Transgene: Tg(En2-lacZ)1Alj  Location: unknown  
Alliance: Tg(En2-lacZ)1Alj page
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Tg(En2-lacZ)1Alj expression driven by 1 gene
 
Mutation detailsThis transgene was made using construct 1 described in figur 1 of the reference that follows. The transgene construct contains a 7 kb genomic fragment, including 6.8 kb of 5' flanking En2 DNA, linked to a bacterial lacZ followed by 1439 bp of 3' En2 genomic DNA which includes 3' untranslated sequence, the polyadenylation signal and 1 kb of 3' flanking sequence. Seven lines are discussed. This particular line is expressed in the cardiac conduction system and is the only one still in existence. (J:4604, J:132789)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:4604 Logan C, et al., Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts. Development. 1993 Mar;117(3):905-16
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory