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Grhl2Gt(RRU622)Byg
Gene trapped Allele Detail
Summary
Symbol: Grhl2Gt(RRU622)Byg
Name: grainyhead like transcription factor 2; gene trap RRU622, BayGenomics
MGI ID: MGI:4340678
Synonyms: Grhl2LacZ4
Gene: Grhl2  Location: Chr15:37233280-37363813 bp, + strand  Genetic Position: Chr15, 14.84 cM, cytoband C
Alliance: Grhl2Gt(RRU622)Byg page
Mutation
origin
Mutant Cell Line:  RRU622
Germline Transmission:  Earliest citation of germline transmission: J:167065
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsTrapped gene association determined by genome coordinate overlap and strand. The gene trap vector was inserted at the beginning of intron 4. No mRNA could be detected in homozygous embryo extracts by RT-PCR. Antibody to the N-terminal region of the protein showed cytoplasmic staining unlike the nuclear staining seen in wild type embryos. (J:167065)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grhl2 Mutation:  41 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory