Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Ero1bGt(P077G11)Wrst Name: endoplasmic reticulum oxidoreductase 1 beta; gene trap P077G11, German Gene Trap Consortium MGI ID: MGI:3864866 Synonyms: ERO1-betai Gene: Ero1b  Location: Chr13:12580701-12624422 bp, + strand  Genetic Position: Chr13, 5.07 cM Alliance: Ero1bGt(P077G11)Wrst page

Diminished insulin stores and mildly disorganized islets in Ero1bGt(P077G11)Wrst/Ero1bGt(P077G11)Wrst mice Show the 1 phenotype image(s) involving this allele.

Mutant Cell Line:	P077G11
Germline Transmission:	Earliest citation of germline transmission: J:158805
Parent Cell Line:	TBV2 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: FlipROSACeoC-2   Mutation details: The gene trap vector inserted into intron 14. Immunohistochemistry confirmed the absence of protein in the islets. (J:158805) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select P077G11 CZ293277 (MGI Seq Detail) 5' RACE multiple * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ero1b Mutation:	25 strains or lines available

Original:	J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:	7 reference(s)