About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:142018 Hager M, et al., Cib2 binds integrin alpha7Bbeta1D and is reduced in laminin alpha2 chain-deficient muscular dystrophy. J Biol Chem. 2008 Sep 5;283(36):24760-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3851442
Gene symbol: Cib2
Gene name: calcium and integrin binding family member 2
Antibody: anti-Cib2
Results
Specimen 3A WT Sarcolemma: postnatal (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Cib2 WT Sarcolemma Expression is at the sarcolemma.

Specimen 3A WT MTJ: postnatal (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Cib2 WT MTJ Expression is at the myotendinous junctions (MTJ).

Specimen 3A WT NMJ: postnatal (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Cib2 WT NMJ Expression is at the neuromuscular junctions (NMJ).

Specimen 3A WT NMJ inset (upper): postnatal (more )
Note: Double labeled: red - Cib2; green - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Cib2 WT NMJ inset Expression is at the neuromuscular junctions (NMJ).

Specimen 3A dy3K Sarcolemma: postnatal; Lama2tm1Stk/Lama2tm1Stk (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Trace 3A Cib2 dy3k Sarcolemma Severe reduction of expression at the sarcolemma.

Specimen 3A dy3K MTJ: postnatal; Lama2tm1Stk/Lama2tm1Stk (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Cib2 dy3k MTJ Mild reduction of expression at the myotendinous junctions (MTJ).

Specimen 3A dy3K NMJ: postnatal; Lama2tm1Stk/Lama2tm1Stk (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Weak 3A Cib2 dy3K NMJ Moderate reduction of expression at the neuromuscular junctions (NMJ).

Specimen 3A dy3K NMJ inset: postnatal; Lama2tm1Stk/Lama2tm1Stk (more )
Note: Double labeled: red - Cib2; green - alpha-bungarotoxin.
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Weak Regionally restricted 3A Cib2 dy3K NMJ inset Moderate reduction of expression at the neuromuscular junctions (NMJ).

Specimen 3A Sarcolemma inset: postnatal (more )
Note: Double labeled: red - Cib2; green - Itga7 (assay MGI:3851441).
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Int7b Sarcolemma inset Expression is at the sarcolemma.

Specimen 3A MTJ inset: postnatal (more )
Note: Double labeled: red - Cib2; green - Itga7 (assay MGI:3851441).
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present Regionally restricted 3A Int7b MTJ inset Expression is at the myotendinous junctions (MTJ).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory