Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gpsm2tm1.1(Venus)Fuma
Name:	G-protein signalling modulator 2 (AGS3-like, C. elegans); targeted mutation 1.1, Fumio Matsuzaki
MGI ID:	MGI:3850859
Synonyms:	Gpsm2tm1.1(YFP)Fuma, LGN-VenusC
Gene:	Gpsm2  Location: Chr3:108585954-108629625 bp, - strand  Genetic Position: Chr3, 47.53 cM, cytoband F3
Alliance:	Gpsm2tm1.1(Venus)Fuma page

Germline Transmission:	Earliest citation of germline transmission: J:132370
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A loxP site and an frt flanked pGKNeo cassette were inserted upstream of exon 13. A modified YFP reporter (Venus) was inserted in frame in exon 15. Mice expressing the fusion protein encoded by this modification were crossed with an unspecified FLP expressing mouse line to excise the neomycin selection cassette. The resulting allele has exons 13 through the coding portion of exon 15 flanked by loxP sites. (J:132370)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gpsm2 Mutation:	26 strains or lines available

Original:	J:132370 Konno D, et al., Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol. 2008 Jan;10(1):93-101
All:	1 reference(s)