Summary | Mutation origin | Mutation description | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Trim21tm1Hm
Name:	tripartite motif-containing 21; targeted mutation 1, Herbert Morse III
MGI ID:	MGI:3849316
Gene:	Trim21  Location: Chr7:102207127-102214689 bp, - strand  Genetic Position: Chr7, 54.76 cM, cytoband F1
Alliance:	Trim21tm1Hm page

Germline Transmission:	Earliest citation of germline transmission: J:149298
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 3 through 5 were replaced with EGFP and a floxed neo cassette. Cre mediated recombination removed the neo cassette. (J:149298)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Trim21tm1Hm

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trim21 Mutation:	25 strains or lines available

Original:	J:149298 Yoshimi R, et al., Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts. J Immunol. 2009 Jun 15;182(12):7527-38
All:	17 reference(s)