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Gene Expression Data
Assay Details
Assay
Reference: J:22020 Cordes SP, et al., The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 1994 Dec 16;79(6):1025-34
Assay type: RNA in situ
MGI Accession ID: MGI:3846736
Gene symbol: Mafb
Gene name: MAF bZIP transcription factor B
Probe: probe X215
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Authors state that identical results were obtained with probe Nco4cks (MGI:1346569).
Results
Specimen 4B upper left: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Weak Regionally restricted 4B upper left Expression at low levels throughout the embryonic headfold and tailbud.

Specimen 4A upper right: embryonic day 8.5; Mafbkr/Mafbkr, a/a (more )
Structure Level Pattern Image Note
TS13: head Weak 4B upper right Low levels of expression in the headfold.
TS13: future hindbrain Absent 4B upper right No expression in the caudal hindbrain.

Specimen 4B lower left: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Weak Regionally restricted 4B lower left Expression at low levels throughout the embryonic headfold and tailbud.

Specimen 4B lower right: embryonic day 8.5; Mafbkr/Mafbkr, a/a (more )
Structure Level Pattern Image Note
TS13: head Weak 4B lower right Low levels of expression in the headfold.
TS13: future hindbrain Absent 4B lower right No expression in the caudal hindbrain.

Specimen not shown: embryonic day 8.5; Mafbkr/Mafb+, a/A (more )
Structure Level Pattern Image Note
TS13: future hindbrain Weak Authors report caudal hindbrain expression consistent with gene dosage.

Specimen 4C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future hindbrain Strong Regionally restricted 4C Restricted domain of high level expression in the caudal hindbrain
TS13: head mesenchyme derived from neural crest Strong Regionally restricted 4C Expression at high levels in a thin stream of neural crest adjacent to the caudal hindbrain.
TS13: ear Absent 4C No expression in the developing otic vesicle.

Specimen 4D: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future hindbrain Strong Regionally restricted 4D Restricted domain of high level expression in the caudal hindbrain

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Weak Authors state that expression fades by the 22- somite stage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory