Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:22020
Cordes SP, et al., The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 1994 Dec 16;79(6):1025-34
|
Assay type:
|
RNA in situ
|
MGI Accession ID:
|
MGI:3846736
|
Gene symbol:
|
Mafb
|
Gene name:
|
MAF bZIP transcription factor B
|
Probe:
|
probe X215
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
Assay notes:
|
Authors state that identical results were obtained with probe Nco4cks (MGI:1346569).
|
|
Results
|
Specimen
4B upper left:
embryonic day 8.5
(more )
Specimen
4B upper left:
(close )
Genetic Background:
|
involves: CD-1 * FVB/N
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: embryo |
Weak |
Regionally restricted |
4B upper left
|
Expression at low levels throughout the embryonic headfold and tailbud.
|
Specimen
4A upper right:
embryonic day 8.5; Mafbkr/ Mafbkr, a/ a
(more )
Specimen
4A upper right:
(close )
Genetic Background:
|
involves: C3H/HeJ
|
Mutant Allele(s):
|
Mafbkr/Mafbkr a/a
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: head |
Weak |
|
4B upper right
|
Low levels of expression in the headfold.
|
TS13: future hindbrain |
Absent |
|
4B upper right
|
No expression in the caudal hindbrain.
|
Specimen
4B lower left:
embryonic day 8.5
(more )
Specimen
4B lower left:
(close )
Genetic Background:
|
involves: CD-1 * FVB/N
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: embryo |
Weak |
Regionally restricted |
4B lower left
|
Expression at low levels throughout the embryonic headfold and tailbud.
|
Specimen
4B lower right:
embryonic day 8.5; Mafbkr/ Mafbkr, a/ a
(more )
Specimen
4B lower right:
(close )
Genetic Background:
|
involves: C3H/HeJ
|
Mutant Allele(s):
|
Mafbkr/Mafbkr a/a
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: head |
Weak |
|
4B lower right
|
Low levels of expression in the headfold.
|
TS13: future hindbrain |
Absent |
|
4B lower right
|
No expression in the caudal hindbrain.
|
Specimen
not shown:
embryonic day 8.5; Mafbkr/Mafb +, a/ A
(more )
Specimen
not shown:
(close )
Genetic Background:
|
involves: C3H/HeJ
|
Mutant Allele(s):
|
Mafbkr/Mafb+ a/A
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: future hindbrain |
Weak |
|
|
Authors report caudal hindbrain expression consistent with gene dosage.
|
Specimen
4C:
embryonic day 8.5
(more )
Specimen
4C:
(close )
Genetic Background:
|
involves: CD-1 * FVB/N
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: future hindbrain |
Strong |
Regionally restricted |
4C
|
Restricted domain of high level expression in the caudal hindbrain
|
TS13: head mesenchyme derived from neural crest |
Strong |
Regionally restricted |
4C
|
Expression at high levels in a thin stream of neural crest adjacent to the caudal hindbrain.
|
TS13: ear |
Absent |
|
4C
|
No expression in the developing otic vesicle.
|
Specimen
4D:
embryonic day 9.0
(more )
Specimen
4D:
(close )
Genetic Background:
|
involves: CD-1 * FVB/N
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: future hindbrain |
Strong |
Regionally restricted |
4D
|
Restricted domain of high level expression in the caudal hindbrain
|
Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
involves: CD-1 * FVB/N
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: embryo |
Weak |
|
|
Authors state that expression fades by the 22- somite stage.
|
|