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Gene Expression Data
Assay Details
Assay
Reference: J:14429 Thomas T, et al., Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo. Exp Cell Res. 1993 Sep;208(1):54-67
Assay type: RNA in situ
MGI Accession ID: MGI:3845870
Gene symbol: Lamb1
Gene name: laminin B1
Probe: Lamb1 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Absent 2B No expression in neural tissue.
TS20: embryo mesenchyme Present Regionally restricted 2B Expression in mesenchyme cells surrounding the central nervous system destined to become the meninges.
TS20: tail myocoele Strong 2B High levels of expression in myotome destined to form skeletal muscle.

Specimen 2F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Weak Regionally restricted 2F Expression in differentiating capillaries.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo mesenchyme Strong Regionally restricted 5B High levels of expression in mesenchyme cells surrounding ganglia.
TS20: dorsal root ganglion Present Regionally restricted 5B Expression in a subset of cells within the ganglia.
TS20: spinal nerve Strong 5B High levels of expression in ganglia fibers and associated nerve roots.
TS20: vertebral cartilage condensation Absent 5B No expression in neural arches.
TS20: tail myocoele Strong 5B High levels of expression in myotome destined to form skeletal muscle.

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral region Strong Regionally restricted 6B High levels of expression in mesenchymal cells of the lower jaw and palate.
TS20: tongue Weak 6B Localized to ectodermal cells forming the outer layer of the tongue.

Specimen 7B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart atrium Present 7B
TS20: heart ventricle Present 7B
TS20: cardiac muscle tissue Strong 7B High levels of expression in myocardial cells
TS20: endocardial lining Present 7B Slightly lower levels in endothelial cells.
TS20: liver Weak 7B

Specimen 8B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach epithelium Strong 8B Uniform high expression in epithelial cells and surrounding mesenchyme.
TS20: stomach mesenchyme Strong 8B Uniform high expression in epithelial cells and surrounding mesenchyme.
TS20: liver Weak Regionally restricted 8B Lower levels of expression in groups of cells in the epithelium and througout the mesenchyme.

Specimen 9B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: metanephros Present Uniform 9B Uniform expression in both epithelial and mesenchymal compartments.
TS20: dorsal aorta Present 9B Expression in the aorta, essentially the same as in surrounding mesenchyme.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory