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Gene Expression Data
Assay Details
Assay
Reference: J:78343 Loebel DA, et al., Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds. Genesis. 2002 Jul;33(3):103-13
Assay type: RNA in situ
MGI Accession ID: MGI:3842740
Gene symbol: Alx4
Gene name: aristaless-like homeobox 4
Probe: Alx4 probe6
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 1d +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head Present Regionally restricted 1d +/+ Expression was detected in the craniofacial tissues.
TS17: somite Present 1d +/+
TS17: forelimb bud Present 1d +/+ FL , 1d +/+
TS17: hindlimb bud Present 1d +/+ HL , 1d +/+
TS17: trunk mesenchyme Present Regionally restricted 1d +/+ Expression was detected in lateral plate mesoderm.
Specimen 1d -/-: embryonic day 10.5; Twist1tm1Bhr/Twist1tm1Bhr (more )
Structure Level Pattern Image Note
TS17: head Weak Regionally restricted 1d -/- Expression was reduced in the craniofacial tissues and lateral plate mesoderm of the mutant.
TS17: trunk mesenchyme Weak Regionally restricted 1d -/- Expression was reduced in the craniofacial tissues and lateral plate mesoderm of the mutant.
TS17: forelimb bud Absent 1d -/- , 1d -/- FL
TS17: hindlimb bud Present 1d -/- , 1d -/- HL Expression in the hindlimb bud was comparable to the wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory