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Use1tm1Aha
Targeted Allele Detail
Summary
Symbol: Use1tm1Aha
Name: unconventional SNARE in the ER 1 homolog (S. cerevisiae); targeted mutation 1, Akihiro Harada
MGI ID: MGI:3842567
Synonyms: p31geo
Gene: Use1  Location: Chr8:71819492-71822376 bp, + strand  Genetic Position: Chr8, 34.43 cM, cytoband C1
Alliance: Use1tm1Aha page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147771
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site followed by a Frt flanked cassette containing an splice acceptor, IRES, betageo, and polyA sequence were inserted into intron 4 and a second loxP site was inserted after exon 8 via homologous recombination. (J:147771)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Use1 Mutation:  18 strains or lines available
References
Original:  J:147771 Uemura T, et al., p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival. Mol Cell Biol. 2009 Apr;29(7):1869-81
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory