Tg(Ctgf-cre)2Aibs
Transgene Detail
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Symbol: |
Tg(Ctgf-cre)2Aibs |
Name: |
transgene insertion 2, Ed Lein |
MGI ID: |
MGI:3838494 |
Synonyms: |
Ctgf-Tg2-Cre |
Transgene: |
Tg(Ctgf-cre)2Aibs Location: unknown
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Alliance: |
Tg(Ctgf-cre)2Aibs page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Ctgf-cre)2Aibs expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Ccn2 (MGI:95537) |
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Mutation details: The 189 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-257E12, containing the entire Ctgf locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Ctgf locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex and hippocampus by the Ctgf promoter/enhancer regions within the BAC transgene.
(J:146821)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ccn2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:146821 Allen Institute for Brain Science, Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS). MGI Direct Data Submission. 2009-04-06; |
All: |
2 reference(s) |
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