Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adrb2tm1Kry
Name:	adrenergic receptor, beta 2; targeted mutation 1, Gerard Karsenty
MGI ID:	MGI:3837346
Synonyms:	Adrb2flox, Adrbeta2-flox
Gene:	Adrb2  Location: Chr18:62310887-62313030 bp, - strand  Genetic Position: Chr18, 35.1 cM
Alliance:	Adrb2tm1Kry page

Germline Transmission:	Earliest citation of germline transmission: J:145998
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 1, and a floxed neo cassette was inserted downstream of exon 1. (J:145998)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adrb2 Mutation:	32 strains or lines available

Original:	J:145998 Hinoi E, et al., The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. J Cell Biol. 2008 Dec 29;183(7):1235-42
All:	20 reference(s)