Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Kat14Gt(OST388291)Lex
Name:	lysine acetyltransferase 14; gene trap OST388291, Lexicon Genetics
MGI ID:	MGI:3836392
Synonyms:	Atac2-
Gene:	Kat14  Location: Chr2:144210952-144249595 bp, + strand  Genetic Position: Chr2, 71.01 cM
Alliance:	Kat14Gt(OST388291)Lex page

Mutant Cell Line:	OST388291
Germline Transmission:	Earliest citation of germline transmission: J:145720
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: The gene trap vector VICTR48, which contains a neo cassette, was inserted downstream of exon 3. The absence of protein was confirmed by western blot analysis on E9.5 embryo extracts. (J:145720) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select OST388291 CG644661 (MGI Seq Detail) 3' RACE Chr2:144231091-144231275 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 6 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Kat14 Mutation:	73 strains or lines available

Original:	J:145720 Guelman S, et al., The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009 Mar;29(5):1176-88
All:	2 reference(s)